Leukaemia and Blood Disorders ( Louise Winteringham and Peter Klinken )

• Analysis of the transcriptional control of red blood cell production (PhD)
• Characterisation of Hls5 knockdown on haemopoiesis (PhD)
• Investigating the effect of hypoxia on blood cell commitment (Honours/PhD)
• Characterise the HLS5 interaction with SMADs in Melanoma (PhD)

Islet Cell Development Program ( Fang-Xu Jiang )

• Understanding the mechanisms of differentiation of islet progenitor Ngn3+ into insulin-secreting beta cells (Honours/PhD)
• Roles of microRNAs on regulating differentiation of embryonic stem cells into pancreatic progenitors (Honours/PhD)
• Investigating roles of novel transcription factors on development of pancreatic lineages (PhD)

Hormone Dependant Cancers

• Defining role of SLIRP in cancer and metabolism (Honours/PhD) ( Peter Leedman, Shane Colley )
• The functional role of miRNAs in human disease (Honours/PhD) ( Peter Leedman, Keith Giles )

Centre for Diabetes Research ( Grant Morahan )

• Systems Genetics of human Type 1 diabetes (T1D) susceptibility genes (Honours/PhD)
• Testing genes in human Type 2 diabetes (T2D) (Honours/PhD)
• Identification of mouse T1D genes (Honours/PhD)
• Molecular genetics of IL12B, a susceptibility gene for many diseases (Honours/PhD)
• The Gene Mine - a revolutionary new genetics resource (Honours/PhD)
• Stem cell research (Honours/PhD)

Centre for Clinical Research In Emergency Medicine ( Simon Brown )

• Anaphylaxis (PhD)
• Head Trauma (PhD)
• Elderly Sepsis (PhD)

Mitochondrial Medicine and Biology ( Aleksandra Filipovska )

• Mitochondrial RNA-binding proteins and their role in mitochondrial gene expression (PhD)
• Development of gene therapy approaches for neurodegenerative diseases caused by mitochondrial dysfunction (PhD)
• Development of tools to study mitochondrial function (PhD)
• Development of new methods for the identification of RNAs bound by mitochondrial RNA-binding proteins (PhD)

Synthetic Biology and Drug Discovery ( Oliver Rackham )

• Re-engineering the genetic code of cells (Honours/PhD)
• Development of synthetic proteins for gene therapy of human diseases (Honours/PhD)
• Development and production of new drugs by re-engineering cell metabolism (Honours/PhD)

Cell Signalling Group ( Evan Ingley )

• Making small proteins to kill cancer and leukaemia cells (PhD)
• A Novel pathway controlling cell shape, movement and metastasis (PhD)
• A Novel pathway controlling nuclear:cytoplasmic shuttling (PhD)
• A proteome-wide analysis of the mammalian SH2-interactome (PhD)

Molecular Endocrinology-GPCRs ( Kevin Pfleger )

• Investigation of G Protein-Coupled Receptor Complexes (Honours)

Cancer Epidemiology ( Lin Fritschi )

• Exposure to occupational carcinogens in migrants to Australia (Honours)
• Arterial calcification in mammograms (Honours)
• Reliability of a questionnaire on shiftwork (Honours)
• Developing a job specific questionnaire (job to be chosen according to the student's interests) (Honours)

Laboratory for Angiogenesis & Tumour Immunology ( Ruth Ganss )

• Role of RGS5 in blood vessel maturation and functionality (Honours/PhD)
• Assess vSMC biology and activity in RGS2 and RGS5 double deficient and RGS5 mutant vSMC (Honours/PhD)
• Role of RGS5 in atherosclerosis (Honours/PhD)

WA Centre for Health and Ageing ( Leon Flicker )

• Healthy Mental Ageing (Honours)
• Depression (Honours)
• Delaying Cognitive Decline (Honours)
• Quality of Life in People with Dementia (Honours)
• Neuroimaging and Structural Brain Disease (Honours)
• Licit Drugs for Older People (Honours)
• Preventing Frailty (Honours)

Cancer Gene Regulation Group ( Archa Fox )

• Structure of the paraspeckle interactome (Honours/PhD)
• How are DBHS proteins targeted to the cell surface in cancer? (Honours/PhD)
• Molecular Mechanisms of the nuclear retention of RNA (Honours/PhD)
• DLX3 - A transcription factor in the spotlight (Honours/PhD)

Endocrinology & Diabetes ( Tom Ratajczak )

• CyP40 regulation of estrogen receptor activity in breast cancer (Honours/PhD)
• CyP40 regulation of androgen receptor activity in prostate cancer (Honours/PhD)
• Sequestosome 1 gene mutations and arsenic in Paget's disease of bone (Honours)
• RECQL4 gene mutations in Rothmund-Thomson Syndrome (Honours)
• The role of the endoplasmic reticulum (ER)-associated protein, OS-9, in primary hyperparathyroidism: correlation of calcium-sensing receptor and OS-9 expression in adenoma tissue (Honours)

Laboratory for Neuromuscular Diseases ( Nigel Laing )

• Next generation sequencing and candidate gene analysis in genetic disorders (Honours/PhD)
• Animal - mouse and ovine models of muscle disease (Honours/PhD)
• Tissue culture models of muscle diseases (Honours/PhD)